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Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5′-Phosphatase (SHIP)
Recently, inhibition of the SH2-containing inositol 5′-phosphatase 1 (SHIP1) has become an attractive strategy for facilitating engraftment of MHC-I mismatched bone marrow grafts, increasing the number of adult stem cells in vivo, and inducing mobilization of hematopoietic stem cells. Utilizing high...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4628863/ https://ncbi.nlm.nih.gov/pubmed/26453006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.09.034 |
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