Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

Broadly neutralizing antibodies (bnAbs) against HIV are believed to be a critical component of the protective responses elicited by an effective HIV vaccine. Neutralizing antibodies against the evolutionarily conserved CD4-binding site (CD4-BS) on the HIV envelope glycoprotein (Env) are capable of i...

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Detaylı Bibliyografya
Asıl Yazarlar: McGuire, Andrew T., Hoot, Sam, Dreyer, Anita M., Lippy, Adriana, Stuart, Andrew, Cohen, Kristen W., Jardine, Joseph, Menis, Sergey, Scheid, Johannes F., West, Anthony P., Schief, William R., Stamatatos, Leonidas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2013
Konular:
Brief Definitive Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620356/
https://ncbi.nlm.nih.gov/pubmed/23530120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122824
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