Knockdown of PPAR δ Gene Promotes the Growth of Colon Cancer and Reduces the Sensitivity to Bevacizumab in Nude Mice Model

The role of peroxisome proliferator – activated receptor- δ (PPAR δ) gene in colon carcinogenesis remains highly controversial. Here, we established nude mice xenograft model using a human colon cancer cell line KM12C either with PPAR δ silenced or normal. The xenografts in PPAR δ-silenced group gre...

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Detalhes bibliográficos
Main Authors: Yang, Lie, Zhou, Jin, Ma, Qin, Wang, Cun, Chen, Keling, Meng, Wenjian, Yu, Yongyang, Zhou, Zongguang, Sun, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620168/
https://ncbi.nlm.nih.gov/pubmed/23593291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060715
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