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NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?

The chemopreventive NO-donating NSAIDs (NO-NSAIDs; NSAIDs with an NO-releasing moiety) modulate PPARδ and offer the opportunity to revisit the controversial role of PPARδ in carcinogenesis (several papers report that PPARδ either promotes or inhibits cancer). This review summarizes the pharmacology...

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Detalhes bibliográficos
Main Authors: Mackenzie, Gerardo G., Rasheed, Shaheen, Wertheim, William, Rigas, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408682/
https://ncbi.nlm.nih.gov/pubmed/18528523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/919572
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