Hippocampal Genetic Knockdown of PPARδ Causes Depression-Like Behaviors and Neurogenesis Suppression

BACKGROUND: Although depression is the leading cause of disability worldwide, its pathophysiology is poorly understood. Our previous study showed that hippocampal peroxisome proliferator-activated receptor δ (PPARδ) overexpression displays antidepressive effect and enhances hippocampal neurogenesis...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Neuropsychopharmacol
Auteurs principaux: Chen, Fang, Yu, Xuben, Meng, Guoliang, Mei, Zhenlin, Du, Yifeng, Sun, Hongbin, Reed, Miranda N, Kong, Lingyi, Suppiramaniam, Vishnu, Hong, Hao, Tang, Susu
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Regular Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545535/
https://ncbi.nlm.nih.gov/pubmed/31038173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyz008
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires