Overexpression of Full-Length Centrobin Rescues Limb Malformation but Not Male Fertility of the Hypodactylous (hd) Rats

Rat hypodactyly (hd) mutation is characterized by abnormal spermatogenesis and sperm decapitation, limb malformation (missing digits II and III) and growth retardation. We have previously reported centrobin (centrosome BRCA2-interacting protein) truncation at the C-terminus in the hd mutant. Here, w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liška, František, Gosele, Claudia, Popova, Elena, Chylíková, Blanka, Křenová, Drahomíra, Křen, Vladimír, Bader, Michael, Tres, Laura L., Hubner, Norbert, Kierszenbaum, Abraham L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620055/
https://ncbi.nlm.nih.gov/pubmed/23577170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060859
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