A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains

Endogenous retroviruses (ERVs) contribute to a range of germline, as well as somatic mutations in mammals. However, autonomous retrotransposition of potentially active elements has not been demonstrated in the rat genome. We cloned an insertion that disrupted the normal splicing of the Cntrob gene t...

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Bibliografiske detaljer
Main Authors: Wang, Yongming, Liška, František, Gosele, Claudia, Šedová, Lucie, Křen, Vladimír, Křenová, Drahomíra, Ivics, Zoltán, Hubner, Norbert, Izsvák, Zsuzsanna
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Letter
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798827/
https://ncbi.nlm.nih.gov/pubmed/19887576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.100073.109
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