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Overexpression of full-length centrobin rescues limb malformation but not male fertility of the hypodactylous (hd) rats.
Rat hypodactyly (hd) mutation is characterized by abnormal spermatogenesis and sperm decapitation, limb malformation (missing digits II and III) and growth retardation. We have previously reported centrobin (centrosome BRCA2-interacting protein) truncation at the C-terminus in the hd mutant. Here, w...
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Главные авторы: | , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science (PLoS)
2013-01-01
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Серии: | PLoS ONE |
Online-ссылка: | http://europepmc.org/articles/PMC3620055?pdf=render |
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