Overexpression of Full-Length Centrobin Rescues Limb Malformation but Not Male Fertility of the Hypodactylous (hd) Rats

Rat hypodactyly (hd) mutation is characterized by abnormal spermatogenesis and sperm decapitation, limb malformation (missing digits II and III) and growth retardation. We have previously reported centrobin (centrosome BRCA2-interacting protein) truncation at the C-terminus in the hd mutant. Here, w...

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Main Authors: Liška, František, Gosele, Claudia, Popova, Elena, Chylíková, Blanka, Křenová, Drahomíra, Křen, Vladimír, Bader, Michael, Tres, Laura L., Hubner, Norbert, Kierszenbaum, Abraham L.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620055/
https://ncbi.nlm.nih.gov/pubmed/23577170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060859
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