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Deficiency of the multi-copy mouse Y gene Sly causes sperm DNA damage and abnormal chromatin packaging
In mouse and man Y chromosome deletions are frequently associated with spermatogenic defects. Mice with extensive deletions of non-pairing Y chromosome long arm (NPYq) are infertile and produce sperm with grossly misshapen heads, abnormal chromatin packaging and DNA damage. The NPYq-encoded multi-co...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619810/ https://ncbi.nlm.nih.gov/pubmed/23178944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.114488 |
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