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Paternal DNA damage resulting from various sperm treatments persists after fertilization and is similar prior and after DNA replication()
In spite of its highly condensed state sperm DNA is vulnerable to damage that can originate from oxidative stress and/or the activity of sperm-specific nucleases. After fertilization, in the oocyte, paternal chromatin undergoes dramatic changes and during this extensive remodeling it can be both rep...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331785/ https://ncbi.nlm.nih.gov/pubmed/21546611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2164/jandrol.111.013532 |
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