Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage

BACKGROUND: Mice with severe non-PAR Y chromosome long arm (NPYq) deficiencies are infertile in vivo and in vitro. We have previously shown that sperm from these males, although having grossly malformed heads, were able to fertilize oocytes via intracytoplasmic sperm injection (ICSI) and yield live...

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Autores principales: Yamauchi, Yasuhiro, Riel, Jonathan M, Stoytcheva, Zoia, Burgoyne, Paul S, Ward, Monika A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911114/
https://ncbi.nlm.nih.gov/pubmed/20573212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-6-r66
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