Deficiency in mouse Y chromosome long arm gene complement is associated with sperm DNA damage

BACKGROUND: Mice with severe non-PAR Y chromosome long arm (NPYq) deficiencies are infertile in vivo and in vitro. We have previously shown that sperm from these males, although having grossly malformed heads, were able to fertilize oocytes via intracytoplasmic sperm injection (ICSI) and yield live...

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Detalhes bibliográficos
Main Authors: Yamauchi, Yasuhiro, Riel, Jonathan M, Stoytcheva, Zoia, Burgoyne, Paul S, Ward, Monika A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911114/
https://ncbi.nlm.nih.gov/pubmed/20573212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-6-r66
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