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Rescue of Sly Expression Is Not Sufficient to Rescue Spermiogenic Phenotype of Mice with Deletions of Y Chromosome Long Arm

Mice with deletions of the Y-specific (non-PAR) region of the mouse Y chromosome long arm (NPYq) have sperm defects and fertility problems that increase proportionally to deletion size. Mice with abrogated function of NPYq-encoded gene Sly (sh367 Sly-KD) display a phenotype similar to that of NPYq d...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Riel, Jonathan M., Yamauchi, Yasuhiro, Ruthig, Victor A., Malinta, Qushay U., Blanco, Mélina, Moretti, Charlotte, Cocquet, Julie, Ward, Monika A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409976/
https://ncbi.nlm.nih.gov/pubmed/30759861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020133
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