Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

Gα-interacting, vesicle-associated protein (GIV/Girdin) is a multidomain signal transducer that enhances PI3K-Akt signals downstream of both G-protein–coupled receptors and growth factor receptor tyrosine kinases during diverse biological processes and cancer metastasis. Mechanistically, GIV serves...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: López-Sánchez, Inmaculada, Garcia-Marcos, Mikel, Mittal, Yash, Aznar, Nicolas, Farquhar, Marilyn G., Ghosh, Pradipta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619294/
https://ncbi.nlm.nih.gov/pubmed/23509302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303392110
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