Accurate SHAPE-directed RNA secondary structure modeling, including pseudoknots

A pseudoknot forms in an RNA when nucleotides in a loop pair with a region outside the helices that close the loop. Pseudoknots occur relatively rarely in RNA but are highly overrepresented in functionally critical motifs in large catalytic RNAs, in riboswitches, and in regulatory elements of viruse...

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Bibliografiske detaljer
Main Authors: Hajdin, Christine E., Bellaousov, Stanislav, Huggins, Wayne, Leonard, Christopher W., Mathews, David H., Weeks, Kevin M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619282/
https://ncbi.nlm.nih.gov/pubmed/23503844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219988110
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