Accurate SHAPE-directed RNA structure determination

Almost all RNAs can fold to form extensive base-paired secondary structures. Many of these structures then modulate numerous fundamental elements of gene expression. Deducing these structure–function relationships requires that it be possible to predict RNA secondary structures accurately. However,...

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Bibliographic Details
Main Authors: Deigan, Katherine E., Li, Tian W., Mathews, David H., Weeks, Kevin M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629221/
https://ncbi.nlm.nih.gov/pubmed/19109441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806929106
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