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USP7 and Daxx regulate mitosis progression and taxane sensitivity by affecting stability of Aurora-A kinase
A large number of patients are resistant to taxane-based chemotherapy. Functional mitotic checkpoints are essential for taxane sensitivity. Thus, mitotic regulators are potential markers for therapy response and could be targeted for anticancer therapy. In this study, we identified a novel function...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619237/ https://ncbi.nlm.nih.gov/pubmed/23348568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.169 |
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