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Targeting uPAR with Antagonistic Recombinant Human Antibodies in Aggressive Breast Cancer

Components of the plasminogen activation system (PAS) which are overexpressed in aggressive breast cancer subtypes offer appealing targets for development of new diagnostics and therapeutics. By comparing gene expression data in patient populations and cultured cell lines, we identified elevated lev...

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Autors principals: LeBeau, Aaron M., Duriseti, Sai, Murphy, Stephanie T., Pepin, Francois, Hann, Byron, Gray, Joe W., VanBrocklin, Henry F., Craik, Charles S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618559/
https://ncbi.nlm.nih.gov/pubmed/23400595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3526
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