Loading...

A New Class of Orthosteric uPAR•uPA Small-Molecule Antagonists Are Allosteric Inhibitors of the uPAR•Vitronectin Interaction

The urokinase receptor (uPAR) is a GPI-anchored cell surface receptor that is at the center of an intricate network of protein-protein interactions. Its immediate binding partners are the serine proteinase urokinase (uPA), and vitronectin (VTN), a component of the extracellular matrix. uPA and VTN b...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Liu, Degang, Zhou, Donghui, Wang, Bo, Knabe, William Eric, Meroueh, Samy O.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654616/
https://ncbi.nlm.nih.gov/pubmed/25671694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500832q
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!