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The Mechanism of Functional Up-Regulation of P2X3 Receptors of Trigeminal Sensory Neurons in a Genetic Mouse Model of Familial Hemiplegic Migraine Type 1 (FHM-1)
A knock-in (KI) mouse model of FHM-1 expressing the R192Q missense mutation of the Cacna1a gene coding for the α1 subunit of Ca(V)2.1 channels shows, at the level of the trigeminal ganglion, selective functional up-regulation of ATP -gated P2X3 receptors of sensory neurons that convey nociceptive si...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2013
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618040/ https://ncbi.nlm.nih.gov/pubmed/23577145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060677 |
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