Inefficient constitutive inhibition of P2X3 receptors by brain natriuretic peptide system contributes to sensitization of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine

BACKGROUND: On trigeminal ganglion neurons, pain-sensing P2X3 receptors are constitutively inhibited by brain natriuretic peptide via its natriuretic peptide receptor-A. This inhibition is associated with increased P2X3 serine phosphorylation and receptor redistribution to non-lipid raft membrane co...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Marchenkova, Anna, Vilotti, Sandra, Ntamati, Niels, van den Maagdenberg, Arn MJM, Nistri, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955999/
https://ncbi.nlm.nih.gov/pubmed/27175010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916646110
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