Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model

BACKGROUND: A genetic knock-in mouse model expressing the R192Q mutation of the α1-subunit of the Ca(V)2.1 channels frequently found in patients with familial hemiplegic migraine shows functional upregulation of ATP-sensitive P2X3 receptors of trigeminal sensory neurons that transduce nociceptive in...

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Autori principali: Gnanasekaran, Aswini, Sundukova, Mayya, van den Maagdenberg, Arn MJM, Fabbretti, Elsa, Nistri, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193817/
https://ncbi.nlm.nih.gov/pubmed/21958474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-77
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