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Effects of LPS on P2X3 receptors of trigeminal sensory neurons and macrophages from mice expressing the R192Q Cacna1a gene mutation of familial hemiplegic migraine-1

A knockin (KI) mouse model with the R192Q missense mutation in the Cacna1a gene commonly detected in familial hemiplegic migraine was used to study whether trigeminal ganglia showed a basal inflammatory profile that could be further enhanced by the lipopolysaccharide (LPS) toxin. Adenosine-5′-tripho...

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Detalhes bibliográficos
Main Authors: Franceschini, Alessia, Hullugundi, Swathi K., van den Maagdenberg, Arn M. J. M., Nistri, Andrea, Fabbretti, Elsa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568424/
https://ncbi.nlm.nih.gov/pubmed/22836594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-012-9328-1
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