Noncontiguous regions in the extracellular domain of EGF receptor define ligand-binding specificity.

Murine epidermal growth factor (EGF) binds with approximately 250-fold higher binding affinity to the human EGF receptor (EGFR) than to the chicken EGFR. This difference in binding affinity enabled the identification of a major ligand-binding domain for EGF by studying the binding properties of vari...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lax, I, Fischer, R, Ng, C, Segre, J, Ullrich, A, Givol, D, Schlessinger, J
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC361798/
https://ncbi.nlm.nih.gov/pubmed/1716463
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires