Noncontiguous regions in the extracellular domain of EGF receptor define ligand-binding specificity.
Murine epidermal growth factor (EGF) binds with approximately 250-fold higher binding affinity to the human EGF receptor (EGFR) than to the chicken EGFR. This difference in binding affinity enabled the identification of a major ligand-binding domain for EGF by studying the binding properties of vari...
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| Vydáno v: | Cell Regul |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Cell Biology
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361798/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1716463/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.2.5.337 |
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