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Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production

Fatty acid synthase (FASN) is a key enzyme in the synthesis of palmitate, the precursor of major nutritional, energetic, and signaling lipids. FASN expression is upregulated in many human cancers and appears to be important for cancer cell survival. Overexpression of FASN has also been found to asso...

詳細記述

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書誌詳細
主要な著者: Liu, Hailan, Wu, Xi, Dong, Zizheng, Luo, Zhiyong, Zhao, Zhenwen, Xu, Yan, Zhang, Jian-Ting
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617951/
https://ncbi.nlm.nih.gov/pubmed/23319743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033811
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