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Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production

Fatty acid synthase (FASN) is a key enzyme in the synthesis of palmitate, the precursor of major nutritional, energetic, and signaling lipids. FASN expression is upregulated in many human cancers and appears to be important for cancer cell survival. Overexpression of FASN has also been found to asso...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Liu, Hailan, Wu, Xi, Dong, Zizheng, Luo, Zhiyong, Zhao, Zhenwen, Xu, Yan, Zhang, Jian-Ting
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Biochemistry and Molecular Biology 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617951/
https://ncbi.nlm.nih.gov/pubmed/23319743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033811
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