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Biosynthesis, isolation, and NMR analysis of leukotriene A epoxides: substrate chirality as a determinant of the cis or trans epoxide configuration
Leukotriene (LT)A(4) and closely related allylic epoxides are pivotal intermediates in lipoxygenase (LOX) pathways to bioactive lipid mediators that include the leukotrienes, lipoxins, eoxins, resolvins, and protectins. Although the structure and stereochemistry of the 5-LOX product LTA(4) is establ...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Biochemistry and Molecular Biology
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617949/ https://ncbi.nlm.nih.gov/pubmed/23242647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033746 |
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