Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

Lipoxygenase (LOX)-catalyzed oxidation of the essential fatty acid, linoleate, represents a vital step in construction of the mammalian epidermal permeability barrier. Analysis of epidermal lipids indicates that linoleate is converted to a trihydroxy derivative by hydrolysis of an epoxy-hydroxy prec...

Full description

Saved in:
Bibliographic Details
Published in:J Lipid Res
Main Authors: Yamanashi, Haruto, Boeglin, William E., Morisseau, Christophe, Davis, Robert W., Sulikowski, Gary A., Hammock, Bruce D., Brash, Alan R.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2018
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880498/
https://ncbi.nlm.nih.gov/pubmed/29459481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082701
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items