The molecular basis of ceramide-1-phosphate recognition by C2 domains

Group IVA cytosolic phospholipase A(2) (cPLA(2)α), which harbors an N-terminal lipid binding C2 domain and a C-terminal lipase domain, produces arachidonic acid from the sn-2 position of zwitterionic lipids such as phosphatidylcholine. The C2 domain has been shown to bind zwitterionic lipids, but mo...

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Bibliografiska uppgifter
Huvudupphovsmän: Ward, Katherine E., Bhardwaj, Nitin, Vora, Mohsin, Chalfant, Charles E., Lu, Hui, Stahelin, Robert V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617939/
https://ncbi.nlm.nih.gov/pubmed/23277511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M031088
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