Differential Roles of Phosphatidylserine, PtdIns(4,5)P(2), and PtdIns(3,4,5)P(3) in Plasma Membrane Targeting of C2 Domains: MOLECULAR DYNAMICS SIMULATION, MEMBRANE BINDING, AND CELL TRANSLOCATION STUDIES OF THE PKCα C2 Domain

Many cytosolic proteins are recruited to the plasma membrane (PM) during cell signaling and other cellular processes. Recent reports have indicated that phosphatidylserine (PS), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)), and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3))...

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Detalhes bibliográficos
Main Authors: Manna, Debasis, Bhardwaj, Nitin, Vora, Mohsin S., Stahelin, Robert V., Lu, Hui, Cho, Wonhwa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533782/
https://ncbi.nlm.nih.gov/pubmed/18621733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802617200
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