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Differential Roles of Phosphatidylserine, PtdIns(4,5)P(2), and PtdIns(3,4,5)P(3) in Plasma Membrane Targeting of C2 Domains: MOLECULAR DYNAMICS SIMULATION, MEMBRANE BINDING, AND CELL TRANSLOCATION STUDIES OF THE PKCα C2 Domain

Many cytosolic proteins are recruited to the plasma membrane (PM) during cell signaling and other cellular processes. Recent reports have indicated that phosphatidylserine (PS), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2)), and phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P(3))...

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Main Authors: Manna, Debasis, Bhardwaj, Nitin, Vora, Mohsin S., Stahelin, Robert V., Lu, Hui, Cho, Wonhwa
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533782/
https://ncbi.nlm.nih.gov/pubmed/18621733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802617200
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