Enhanced Fracture Repair by Leukotriene Antagonism Is Characterized by Increased Chondrocyte Proliferation and Early Bone Formation: A Novel Role of the Cysteinyl LT-1 Receptor

Inflammatory mediators and drugs which affect inflammation can influence the healing of injured tissues. Leukotrienes are potent inflammatory mediators, and similar to prostaglandins, are metabolites of arachidonic acid which can have positive or negative effects on bone and cartilage tissues. Here...

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Main Authors: WIXTED, JOHN J., FANNING, PAUL J., GAUR, TRIPTI, O’CONNELL, SHANNON L., SILVA, JASON, MASON-SAVAS, APRIL, AYERS, DAVID C., STEIN, GARY S., LIAN, JANE B.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617560/
https://ncbi.nlm.nih.gov/pubmed/19544365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21809
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