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Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Cysteinyl-leukotrienes (cys-LTs) are 5-lipoxygenase-derived lipid mediators involved in the pathogenesis and progression of inflammatory disorders, in particular asthma. We have previously found evidence linking these mediators to increased levels of proteolytic enzymes in tissue specimens of human...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Di Gennaro, Antonio, Araújo, Ana Carolina, Busch, Albert, Jin, Hong, Wågsäter, Dick, Vorkapic, Emina, Caidahl, Kenneth, Eriksson, Per, Samuelsson, Bengt, Maegdefessel, Lars, Haeggström, Jesper Z.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828611/
https://ncbi.nlm.nih.gov/pubmed/29432192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717906115
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