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Cysteinyl leukotriene receptor 1 antagonism prevents experimental abdominal aortic aneurysm

Cysteinyl-leukotrienes (cys-LTs) are 5-lipoxygenase-derived lipid mediators involved in the pathogenesis and progression of inflammatory disorders, in particular asthma. We have previously found evidence linking these mediators to increased levels of proteolytic enzymes in tissue specimens of human...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Di Gennaro, Antonio, Araújo, Ana Carolina, Busch, Albert, Jin, Hong, Wågsäter, Dick, Vorkapic, Emina, Caidahl, Kenneth, Eriksson, Per, Samuelsson, Bengt, Maegdefessel, Lars, Haeggström, Jesper Z.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828611/
https://ncbi.nlm.nih.gov/pubmed/29432192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717906115
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