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Leukotriene A(4) hydrolase: Selective abrogation of leukotriene B(4) formation by mutation of aspartic acid 375
Leukotriene A(4) (LTA(4), 5S-trans-5,6-oxido-7,9-trans-11,14-cis-eicosatetraenoic acid) hydrolase (LTA4H)/aminopeptidase is a bifunctional zinc metalloenzyme that catalyzes the final and rate-limiting step in the biosynthesis of leukotriene B(4) (LTB(4), 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosate...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123628/ https://ncbi.nlm.nih.gov/pubmed/11917124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072090099 |
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