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Proline Facilitates Membrane Insertion of the Antimicrobial Peptide Maculatin 1.1 via Surface Indentation and Subsequent Lipid Disordering

The role of proline in the disruption of membrane bilayer structure upon antimicrobial peptide (AMP) binding was studied. Specifically, (31)P and (2)H solid-state NMR and dual polarization interferometry (DPI) were used to analyze the membrane interactions of three AMPs: maculatin 1.1 and two analog...

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Main Authors: Fernandez, David I., Lee, Tzong-Hsien, Sani, Marc-Antoine, Aguilar, Marie-Isabel, Separovic, Frances
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617439/
https://ncbi.nlm.nih.gov/pubmed/23561526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.059
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