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Coarse-Grained Simulations of the Membrane-Active Antimicrobial Peptide Maculatin 1.1

Maculatin 1.1 (M1.1) is a membrane-active antimicrobial peptide (AMP) from an Australian tree frog that forms a kinked amphipathic α-helix in the presence of a lipid bilayer or bilayer-mimetic environment. To help elucidate its mechanism of membrane-lytic activity, we performed a total of ∼8 μs of c...

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Hlavní autoři: Bond, Peter J., Parton, Daniel L., Clark, James F., Sansom, Mark S. P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553143/
https://ncbi.nlm.nih.gov/pubmed/18641064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.128686
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