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Maculatin 1.1 Disrupts Staphylococcus aureus Lipid Membranes via a Pore Mechanism
Maculatin 1.1 (Mac1) showed potent activity against Staphylococcus aureus with an MIC of 7 μM. The mode of action of Mac1 was investigated by combining assays with S. aureus cells and lipid vesicles mimicking their membrane composition. A change in Mac1 conformation was monitored by circular dichroi...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719708/ https://ncbi.nlm.nih.gov/pubmed/23689707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00195-13 |
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