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A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

We describe a microbial flow cytometry method that quantifies within 3 hours antimicrobial peptide (AMP) activity, termed Minimum Membrane Disruptive Concentration (MDC). Increasing peptide concentration positively correlates with the extent of bacterial membrane disruption and the calculated MDC is...

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Bibliographic Details
Published in:PLoS One
Main Authors: O’Brien-Simpson, Neil M., Pantarat, Namfon, Attard, Troy J., Walsh, Katrina A., Reynolds, Eric C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4795541/
https://ncbi.nlm.nih.gov/pubmed/26986223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151694
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