CD160Ig Fusion Protein Targets a Novel Costimulatory Pathway and Prolongs Allograft Survival

CD160 is a cell surface molecule expressed by most NK cells and approximately 50% of CD8(+) cytotoxic T lymphocytes. Engagement of CD160 by MHC class-I directly triggers a costimulatory signal to TCR-induced proliferation, cytokine production and cytotoxic effector functions. The role of CD160 in al...

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Main Authors: D’Addio, Francesca, Ueno, Takuya, Clarkson, Michael, Zhu, Baogong, Vergani, Andrea, Freeman, Gordon J., Sayegh, Mohamed H., Ansari, Mohammed Javeed I., Fiorina, Paolo, Habicht, Antje
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617215/
https://ncbi.nlm.nih.gov/pubmed/23593209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060391
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