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CD160Ig Fusion Protein Targets a Novel Costimulatory Pathway and Prolongs Allograft Survival
CD160 is a cell surface molecule expressed by most NK cells and approximately 50% of CD8(+) cytotoxic T lymphocytes. Engagement of CD160 by MHC class-I directly triggers a costimulatory signal to TCR-induced proliferation, cytokine production and cytotoxic effector functions. The role of CD160 in al...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3617215/ https://ncbi.nlm.nih.gov/pubmed/23593209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060391 |
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