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A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy
T-bet plays a crucial role in Th1 development. We investigated the role of T-bet in the development of allograft rejection in an established MHC class II–mismatched (bm12 into B6) model of chronic allograft vasculopathy (CAV). Intriguingly, and in contrast to IFN-γ(−/−) mice that are protected from...
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| Asıl Yazarlar: | , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605226/ https://ncbi.nlm.nih.gov/pubmed/19047438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081937 |
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