Prolonged, Low-Dose Anti-Thymocyte Globulin, Combined with CTLA4-Ig, Promotes Engraftment in a Stringent Transplant Model

BACKGROUND: Despite significant nephrotoxicity, calcineurin inhibitors (CNIs) remain the cornerstone of immunosuppression in solid organ transplantation. We, along with others, have reported tolerogenic properties of anti-thymocyte globulin (ATG, Thymoglobulin®), evinced by its ability both to spare...

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Autors principals: D’Addio, Francesca, Boenisch, Olaf, Magee, Ciara N., Yeung, Melissa Y., Yuan, Xueli, Mfarrej, Bechara, Vergani, Andrea, Ansari, Mohammed Javeed, Fiorina, Paolo, Najafian, Nader
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542267/
https://ncbi.nlm.nih.gov/pubmed/23326509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053797
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