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TIM-3: A Novel Regulatory Molecule of Alloimmune Activation

T cell Ig domain and mucin domain (TIM)-3 has previously been established as a central regulator of Th1 responses and immune tolerance. In this study, we examined its functions in allograft rejection in a murine model of vascularized cardiac transplantation. TIM-3 was constitutively expressed on den...

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Detalhes bibliográficos
Main Authors: Boenisch, Olaf, D’Addio, Francesca, Watanabe, Toshihiko, Elyaman, Wassim, Magee, Ciara N., Yeung, Melissa Y., Padera, Robert F., Rodig, Scott J., Murayama, Takaya, Tanaka, Katsunori, Yuan, Xueli, Ueno, Takuya, Jurisch, Anke, Mfarrej, Bechara, Akiba, Hisaya, Yagita, Hideo, Najafian, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619947/
https://ncbi.nlm.nih.gov/pubmed/20956339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903435
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