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The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race and sex

BACKGROUND: Cotinine, a nicotine metabolite, is a biomarker of tobacco, nicotine and carcinogen exposure. However a given cotinine level may not represent the same tobacco exposure; for example, African Americans have higher cotinine levels than Caucasians after controlling for exposure. METHODS: Co...

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Detalhes bibliográficos
Main Authors: Zhu, Andy Z.X., Renner, Caroline C., Hatsukami, Dorothy K., Swan, Gary E., Lerman, Caryn, Benowitz, Neal L., Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617060/
https://ncbi.nlm.nih.gov/pubmed/23371292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-1234-T
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