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CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people

OBJECTIVES: Alaska Native people (AN) have a high prevalence of tobacco use and associated morbidity and mortality when compared to the general U.S. population. Variation in the CYP2A6 and CYP2B6 genes, encoding enzymes responsible for nicotine metabolic inactivation and procarcinogen activation, ha...

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Detalhes bibliográficos
Main Authors: Binnington, Matthew J., Zhu, Andy Z.X., Renner, Caroline C., Lanier, Anne P., Hatsukami, Dorothy K., Benowitz, Neal L, Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349071/
https://ncbi.nlm.nih.gov/pubmed/22569203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283527c1c
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