Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level

BACKGROUND: Variability in smoking behavior is partly attributable to heritable individual differences in nicotine clearance rates. This can be assessed as the ratio of the metabolites cotinine (COT) and 3'-hydroxycotinine (3HC) (referred to as the nicotine metabolism ratio, NMR). We hypothesiz...

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Detalhes bibliográficos
Main Authors: Strasser, Andrew A., Benowitz, Neal L., Pinto, Angela G., Tang, Kathy Z., Hecht, Stephen S., Carmella, Steve G., Tyndale, Rachel F., Lerman, Caryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077576/
https://ncbi.nlm.nih.gov/pubmed/21212060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0674
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