Association of the Nicotine Metabolite Ratio and CHRNA5/CHRNA3 Polymorphisms With Smoking Rate Among Treatment-Seeking Smokers

INTRODUCTION: Genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in the CHRNA5/A3/B4 gene cluster with heaviness of smoking. The nicotine metabolite ratio (NMR), a measure of the rate of nicotine metabolism, is associated with the number of cigarettes per day (CPD) an...

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Main Authors: Falcone, Mary, Jepson, Christopher, Benowitz, Neal, Bergen, Andrew W., Pinto, Angela, Wileyto, E. Paul, Baldwin, Don, Tyndale, Rachel F., Lerman, Caryn, Ray, Riju
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103715/
https://ncbi.nlm.nih.gov/pubmed/21385908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntr012
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