Association of the Nicotine Metabolite Ratio and CHRNA5/CHRNA3 Polymorphisms With Smoking Rate Among Treatment-Seeking Smokers

INTRODUCTION: Genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in the CHRNA5/A3/B4 gene cluster with heaviness of smoking. The nicotine metabolite ratio (NMR), a measure of the rate of nicotine metabolism, is associated with the number of cigarettes per day (CPD) an...

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Bibliographic Details
Main Authors:	Falcone, Mary, Jepson, Christopher, Benowitz, Neal, Bergen, Andrew W., Pinto, Angela, Wileyto, E. Paul, Baldwin, Don, Tyndale, Rachel F., Lerman, Caryn, Ray, Riju
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2011
Subjects:	Brief Reports
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3103715/ https://ncbi.nlm.nih.gov/pubmed/21385908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntr012
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Association of the Nicotine Metabolite Ratio and CHRNA5/CHRNA3 Polymorphisms With Smoking Rate Among Treatment-Seeking Smokers

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