Nicotine Metabolite Ratio: Comparison of the Three Urinary Versions to the Plasma Version and Nicotine Clearance in Three Clinical Studies

BACKGROUND: Variation in CYP2A6 activity influences tobacco smoking behaviors and smoking-related health outcomes. Plasma Nicotine Metabolite Ratio (NMR) is a robust phenotypic biomarker of CYP2A6 activity and nicotine clearance. In urine, the NMR has been calculated as a ratio of free trans-3’-hydr...

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Publicado no:Drug Alcohol Depend
Main Authors: Giratallah, Haidy K., Chenoweth, Meghan J., Addo, Newton, Ahluwalia, Jasjit S., Cox, Lisa Sanderson, Lerman, Caryn, George, Tony P., Benowitz, Neal L, Tyndale, Rachel F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8133391/
https://ncbi.nlm.nih.gov/pubmed/33873029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2021.108708
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