Preclinical and Clinical Evaluation of Intraductally Administered Agents in Early Breast Cancer

Most breast cancers originate in the epithelial cells lining the breast ducts. Intraductal administration of cancer therapeutics would lead to high drug exposure to ductal cells and eliminate preinvasive neoplasms while limiting systemic exposure. We performed preclinical studies in N-methyl-N’-nitr...

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Autors principals: Stearns, Vered, Mori, Tsuyoshi, Jacobs, Lisa K., Khouri, Nagi F., Gabrielson, Edward, Yoshida, Takahiro, Kominsky, Scott L., Huso, David L., Jeter, Stacie, Powers, Penny, Tarpinian, Karineh, Brown, Regina J., Lange, Julie R., Rudek, Michelle A., Zhang, Zhe, Tsangaris, Theodore N., Sukumar, Saraswati
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616888/
https://ncbi.nlm.nih.gov/pubmed/22030751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002368
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