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Intraductally administered pegylated liposomal doxorubicin reduces mammary stem cell function in the mammary gland but in the long term, induces malignant tumors

Previously, we have shown that the intraductal (i.duc) administration of pegylated liposomal doxorubicin (PLD) to Her2/neu transgenic mice is associated with mammary tumor regression and prevention. Exploring the mechanism underlying the protection afforded by PLD, we studied: the effects of i.duc P...

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Detalhes bibliográficos
Main Authors: Chun, Yong Soon, Yoshida, Takahiro, Mori, Tsuyoshi, Huso, David L., Zhang, Zhe, Stearns, Vered, Perkins, Brandy, Jones, Richard J., Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478104/
https://ncbi.nlm.nih.gov/pubmed/22752247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2138-x
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